PharmacyCodes



Nitrendipino [Inn-Spanish] en es it fr

Nitrendipino [Inn-Spanish] Brand names, Nitrendipino [Inn-Spanish] Analogs

Nitrendipino [Inn-Spanish] Brand Names Mixture

  • No information avaliable

Nitrendipino [Inn-Spanish] Chemical_Formula

C18H20N2O6

Nitrendipino [Inn-Spanish] RX_link

No information avaliable

Nitrendipino [Inn-Spanish] fda sheet

Nitrendipino [Inn-Spanish] msds (material safety sheet)

Nitrendipino [Inn-Spanish] Synthesis Reference

H. Meyar et al., Ger. pat 2117571; eidem, US pat. 3799934

Nitrendipino [Inn-Spanish] Molecular Weight

360.361 g/mol

Nitrendipino [Inn-Spanish] Melting Point

156-160 oC

Nitrendipino [Inn-Spanish] H2O Solubility

Insoluble

Nitrendipino [Inn-Spanish] State

Solid

Nitrendipino [Inn-Spanish] LogP

2.756

Nitrendipino [Inn-Spanish] Dosage Forms

No information avaliable

Nitrendipino [Inn-Spanish] Indication

For the treatment of mild to moderate hypertension

Nitrendipino [Inn-Spanish] Pharmacology

Nitrendipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nitrendipine is similar to other peripheral vasodilators. Nitrendipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Nitrendipino [Inn-Spanish] Absorption

No information avaliable

Nitrendipino [Inn-Spanish] side effects and Toxicity

No information avaliable

Nitrendipino [Inn-Spanish] Patient Information

No information avaliable

Nitrendipino [Inn-Spanish] Organisms Affected

Humans and other mammals